HC: Frank Reich
OC: Marcus Brady
DC: Gus Bradley
Depth Chart:
QB: Matt Ryan
Sam Ehlinger, James Morgan, Jack Coan (R)
RB: Jonathan Taylor
Nyheim Hines, Deon Jackson, D’vonte Price (R), CJ Verdell (R), Max Borghi (R), Jah-Maine Martin (R)
WR: Michael Pittman Jr., Alec Pierce (R), Parris Campbell
Keke Coutee, Ashton Dulin, Dezmon Patmon, Mike Strachan, De’Michael Harris, Samson Nacua (R), Kekoa Crawford (R), Michael Young Jr. (R)
TE: Mo Alie-Cox
Kylen Granson, Jelani Woods (R), Andrew Ogletree (R), Nikola Kalinic, Michael Jacobson, Farrod Green, Eli Wolf
2022 Draft Class:
| Pick | Overall | Pos. | Player | Team | College |
| 2.21 | 53 | WR | Alec Pierce | IND | Cinicnnati |
| 3.09 | 73 | TE | Jelani Woods | IND | Virginia |
| 3.13 | 77 | OT | Bernhard Raimann | IND | Central Michigan |
| 3.32 | 96 | S | Nick Cross | IND | Maryland |
| 5.16 | 159 | DT | Eric Johnson | IND | Missouri State |
| 6.13 | 192 | TE | Andrew Ogletree | IND | Youngstown State |
| 6.37 | 216 | DT | Curtis Brooks | IND | Cincinnati |
| 7.18 | 239 | S | Rodney Thomas II | IND | Yale |
2021 Draft Class:
| Pick | Overall | Pos. | Player | Team | College |
| 1.21 | 21 | DE2 | Kwity Paye | IND | Michigan |
| 2.22 | 54 | DE8 | Daye Odeyingbo | IND | Vanderbilt |
| 4.22 | 127 | TE7 | Kylen Granson | IND | SMU |
| 5.21 | 165 | S12 | Shawn Davis | IND | Florida |
| 6.34 | 218 | QB10 | Sam Ehlinger | IND | Texas |
| 7.01 | 229 | WR32 | Mike Strachan | IND | Charleston |
| 7.20 | 248 | OG14 | Will Fries | IND | Penn State |
2020 Draft Class:
| Pick | Overall | Position | Player | College |
| 2.02 | 34 | WR | Michael Pittman Jr. | USC |
| 2.09 | 41 | RB | Jonathan Taylor | Wisconsin |
| 3.21 | 85 | S | Julian Blackmon | Utah |
| 4.16 | 122 | QB | Jacob Eason | Washington |
| 5.03 | 149 | G | Danny Pinter | Ball State |
| 6.14 | 193 | DT | Rob Windsor | Penn State |
| 6.32 | 211 | CB | Isaiah Rodgers | Massachusetts |
| 6.33 | 212 | WR | Dezmon Patmon | Washington State |
| 6.34 | 213 | LB | Jordan Glasgow | Michigan |