HC: Matt Eberflus
OC: Luke Getsy
DC: Alan Williams
Depth Chart:
QB: Justin Fields
Trevor Siemian, Ryan Willis
RB: David Montgomery
Khalil Herbert, Darrynton Evans, Trestan Ebner (R), Master Teague III
FB: Khari Blasingame
WR: Darnell Mooney, Byron Pringle, Velus Jones, Jr.
Equanimeous St. Brown, David Moore, Daz Newsome, Isaiah Coulter, Nsimba Webster, Chris Finke, Landon Lenoir (R), Cyrus Holder (R), Kevin Shaa (R), Savon Scarver (R), Luke Little (R), Henry Litwin (R)
TE: Cole Kmet
James O’Shaughnessy, Ryan Griffin, Jesper Horsted, Jake Tonges (R), Chase Allen (R)
2022 Draft Class:
| Pick | Overall | Pos. | Player | Team | College |
| 2.07 | 39 | CB | Kyler Gordon | CHI | Washington |
| 2.16 | 48 | S | Jaquan Brisker | CHI | Penn State |
| 3.07 | 71 | WR | Velus Jones Jr. | CHI | Tennessee |
| 5.25 | 168 | IT | Braxton Jones | CHI | Southern Utah |
| 5.31 | 174 | DE | Dominique Robinson | CHI | Miami OH |
| 6.07 | 186 | OT | Zacharay Thomas | CHI | San Diego State |
| 6.24 | 203 | RB | Trestan Ebner | CHI | Baylor |
| 6.28 | 207 | C | Doug Kramer | CHI | Illinois |
| 7.05 | 226 | OG | Ja’Tyre Carter | CHI | Southern |
| 7.33 | 254 | S | Elijah Hicks | CHI | California |
| 7.34 | 255 | P | Trenton Gill | CHI | NC State |
2021 Draft Class:
| Pick | Overall | Pos. | Player | Team | College |
| 1.11 | 11 | QB4 | Justin Fields | CHI | Ohio State |
| 2.07 | 39 | OT5 | Teven Jenkins | CHI | Oklahoma State |
| 5.07 | 151 | OT18 | Larry Borom | CHI | Missouri |
| 6.33 | 217 | RB14 | Khalil Herbert | CHI | Virginia Tech |
| 6.37 | 221 | WR31 | Dazz Newsome | CHI | UNC |
| 6.44 | 228 | CB35 | Thomas Graham Jr. | CHI | Oregon |
| 7.22 | 250 | DT19 | Khyiris Tonga | CHI | BYU |
2020 Draft Class:
| Pick | Overall | Position | Player | College |
| 2.11 | 43 | TE | Cole Kmet | Notre Dame |
| 2.18 | 50 | CB | Jaylon Johnson | Utah |
| 5.10 | 155 | DE | Trevis Gipson | Tulsa |
| 5.28 | 173 | WR | Darnell Mooney | Tulane |
| 7.12 | 226 | G | Arlington Hamrbight | Colorado |
| 7.13 | 227 | G | Lachavious Simmons | Tennessee State |