HC: Kliff Kinsgbury
OC: Sean Kugler
DC: Vance Joseph
Depth Chart:
QB: Kyler Murray
Colt McCoy, Trace McSorley
RB: James Conner
Darrel Williams, Eno Benjamin, Keaontay Ingram (R), Jonathan Ward, Jaylen Samuels
WR: DeAndre Hopkins, Marquise Brown
AJ Green, Rondale Moore, Andy Isabella, Antoine Wesley, Andre Baccellia, Greg Dortch, Changa Hodge (R), JaVonta Payton (R), Jontre Kirklin (R), Stephon Robinson Jr. (R)
TE: Zach Ertz
Trey McBride (R), Maxx Williams, Stephen Anderson, David Wells, Deon Yelder, Alex Ellis, Bernhard Seikovits, Chris Pierce Jr. (R)
2022 Draft Class:
| Pick | Overall | Pos. | Player | Team | College |
| 2.23 | 55 | TE | Trey McBride | ARI | Colorado State |
| 3.23 | 87 | DE | Cameron Thomas | ARI | San Diego State |
| 3.36 | 100 | DE | Myjai Sanders | ARI | Cincinnati |
| 6.22 | 201 | RB | Keaontay Ingram | ARI | USC |
| 6.36 | 215 | OG | Lecitus Smith | ARI | Virginia Tech |
| 7.23 | 244 | CB | Christian Matthew | ARI | Valdosta State |
| 7.35 | 256 | LB | Jesse Luketa | ARI | Penn State |
| 7.36 | 257 | OG | Marquis Hayes | ARI | Oklahoma |
2021 Draft Class:
| Pick | Overall | Pos. | Player | Team | College |
| 1.16 | 16 | LB2 | Zaven Collins | ARI | Tulsa |
| 2.17 | 49 | WR7 | Rondale Moore | ARI | Purdue |
| 4.31 | 136 | CB21 | Marco Wilson | ARI | Florida |
| 6.26 | 210 | DE27 | Victor Dimukeje | ARI | Duke |
| 6.39 | 223 | CB33 | Tay Gowan | ARI | UCF |
| 7.15 | 243 | S21 | James Wiggins | ARI | Cincinatti |
| 7.19 | 247 | C8 | Michael Menet | ARI | Penn State |
2020 Draft Class:
| Pick | Overall | Position | Player | College |
| 1.08 | 8 | LB | Isaiah Simmons | Clemson |
| 3.08 | 72 | T | Josh Jones | Houston |
| 4.08 | 114 | DT | Leki Fotu | Utah |
| 4.25 | 131 | DT | Rashard Lawrence | LSU |
| 6.23 | 202 | LB | Evan Weaver | California |
| 7.08 | 222 | RB | Eno Benjamin | Arizona State |